ABSTRACT
This case control study was conducted in the department of Gynae & Obstetrics, Sir Salimullah Medical College & Mitford Hospital (SSMC & MH), Dhaka, during the period of January 2008 to December 2008 to compare the length of operation, blood loss, length of hospital stay, drug requirements for pain and post-operative pain and activity levels between Laparoscopically Assisted Vaginal Hysterectomy (LAVH) & Total Abdominal Hysterectomy (TAH). A total of 50 patients who met some eligibility criteria were consecutively included in the study and matched in a case control manner for age, weight, diagnosis & uterine size. The procedures were performed by the same surgeon. On average, LAVH operations took significantly longer than TAH operations (P<0.001). Equal number of patients of both groups (40%) needed blood transfusion. No significant difference about haemoglobin level compared to TAH group on 3rd POD (P=0.246). However total amount of analgesics needed was much higher in the TAH group than that of the LAVH group (243.7 ± 40.3VS 182.1 ± 69.6 mg; P= 0.005) and the total cost of operation was significantly less in the TAH group (4500 ± 500 takas) than in the LAVH group (6500 ± 500 taka) (P<0.001). It was observed that LAVH group produced earlier relief from pain in terms of pain VAS on 3rd POD, (P<0.001). LAVH is less painful, has a shorter length of hospital stay and quicker return to work than TAH. Moreover LAVH does not increase intra or postoperative complications.
ABSTRACT
Preeclampsia is a pregnancy specific, multi-system disorder of unknown etiology characterized by new onset of elevated blood pressure & proteinuria after 20 weeks of gestation. Globally preeclampsia and other hypertensive disorders of pregnancy are a leading cause of maternal and infant illness and death. But the exact pathophysiology is yet to be explored. It was a case control study and was conducted during the period of January 2010 - December 2010 in the department of Obs & Gynae DMCH and dept. of Biochemistry of BSMMU. The main objective of the study was to evaluate the association of serum ferritin and iron in preeclampsia & eclampsia. A total 100 pregnant women were included in this study. Of them 50 preeclamptic or eclamptic, nonanaemic patients not in labour (26-40weeks) were taken as case and 50 normotensive pregnant women were taken as control. Mean Serum ferritin level in case and control group was 100.03 ± 123.52 μgm/L and 31.53 ± 20.86 μgm/L respectively which is highly significant (P< 0.001). Out of 50 cases ferritin level was raised in 10 cases (20%). In 80% cases ferritin level was below the cut-off value that is normal or below normal but in 100% of controls had ferritin level below the cut off value.